Kuhner Shaker Bioprocessing Mini Conference at BTEC

Shaken Cultivations: Scale-up, Scale Down and Automation

About this Event
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Welcome to the Kuhner Shaker BTEC Mini Conference!

Join us on Wed October 15th at NC State University's BTEC facilities for a full scientific program as we explore what makes for successful cell cultivations at any scale with a focus on automation and process optimization. Ample networking and learning opportunities are included during lunch and refreshment breaks. We will also have an opportunity to take a tour of BTEC's state of the art training facilities and learn about what they have to offer to students and industrial groups in the Raleigh area.

Whether you're a seasoned professional or just starting out in the field, there's something for everyone at the Kuhner Shaker BTEC Mini Conference.

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Who should participate?

In addition to the scientific program and networking opportunities, the day will be particularly useful to those cultivating mammalian and microbial cells using shakers. This includes cell biologists, bioengineers, cell culture and fermentation scientists, chemical engineers in research and development, process development, technology transfer and associated management roles.

We will review how adjustments made to shaker attributes (e.g. speed, diameter, humidification), vessel attributes (e.g. size, shape, fill volume, feeding, construction material, baffling systems, closure shape and type) and vessel selection (e.g. well plates, tubes, flasks, bioreactors) must be considered together. We will discuss how changes to any of these variables impact the scalability of cultivation results.

For 2025 we will be further focusing on automation of shaker-scale cultivations and will highlight innovations in automation and control of your workflows.

At the end of the program, participants will have a thorough understanding of how to impact desired changes in mixing times, kLa and shear stress (incl. liquid velocity) across a multi-scale cultivation system. No advanced training necessary. Knowledge about your current cultivation practices and culture needs will be helpful during question-and-answer periods.

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Sample Agenda


🕑: 11:30 AM - 12:00 PM
Badge Pickup

🕑: 12:00 PM - 12:15 PM
Lunch Pickup

Info: Lunch will be served prior to opening remarks. Guests are invited to enjoy throughout the presentations.

🕑: 12:15 PM - 12:45 PM
Introduction from BTEC Staff and Kuhner Opening Remarks
Host: BTEC Staff/Bob Keohane, Kuhner Shaker

🕑: 12:45 PM - 01:30 PM
Engineering Parameters of Shaken Cultivation Systems
Host: Dave Laidlaw, Kuhner Shaker

🕑: 01:30 PM - 01:50 PM
Advanced Cultivation in Microtiter Plates
Host: Zack Scheuermann, Kuhner Shaker

🕑: 01:50 PM - 02:15 PM
Group 1 BTEC Tour/Group 2 Refreshment Break

🕑: 02:15 PM - 02:40 PM
Group 2 BTEC Tour/Group 1 Refreshment Break

🕑: 02:40 PM - 03:15 PM
Automated Solutions for Shaken Cultivations
Host: Bob Keohane, Kuhner Shaker

🕑: 03:15 PM - 03:45 PM
Off-Gas Analysis and Fed-Batch Optimization Tools
Host: Zack Scheuermann, Kuhner Shaker

🕑: 03:45 PM - 04:00 PM
Closing Remarks
Host: Bob Keohane, Kuhner Shaker

🕑: 04:00 PM - 05:30 PM
Free Happy Hour at Sammy's Tap & Grill

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