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Follow 3001 Nightlife3 Nightclubs in one! For over 35 years as Myrtle Beach's Entertainment Venue, 2001 is back as 3001 Nightlife. Billed as the largest nightlife and entertainment venue in South Carolina – the building features three rooms, three dance floors and five bars, and each room has a different theme, live music, DJs, VIPs, bottle service and so much more! 3001 Nightlife couples state of the art sound with lighting and 4K video capabilities.