You probably think of DNA as life's blueprint—the famous double helix storing your genetic code. But what if I told you that certain DNA strands can actually work as tiny molecular machines, hunting down invisible toxins in your bloodstream like microscopic bounty hunters?
Welcome to the world of DNAzymes—single-stranded DNA molecules that have learned a remarkable new trick: acting as catalytic enzymes. These molecular Swiss Army knives are being programmed to tackle everything from cancer diagnostics to environmental monitoring. But here's where it gets personal: they might just solve one of public health's most insidious problems—the silent epidemic of heavy metal poisoning that current testing methods are too slow and expensive to catch.
Think lead contamination is a problem of the past? Think again. From Bangkok's aging water pipes to industrial runoff, heavy metals remain an invisible threat. Traditional testing means sending samples to labs, waiting days for results, and paying hefty fees—a bottleneck that leaves communities vulnerable. But what if you could test for lead as easily as checking pH with a strip of paper?
Enter Dr. Paskorn Muangphrom, a molecular detective from KMUTT who traded traditional yeast engineering for the cutting edge of biosensor technology. After years perfecting enzyme functions in E. coli (yes, bacteria can be surprisingly helpful colleagues), he's now leading the charge to democratize health monitoring. His journey from NMR spectroscopy wizard to biosensor innovator reflects a broader shift in Thai science—from pure research to practical solutions for real communities.
Dr. Muangphrom will reveal how his lab has engineered DNAzyme biosensors that can detect lead ions with a simple color change—no lab required, no PhD needed to read the results. We'll explore how these paper-based detectives work, why they're selective enough to ignore other metals, and how they could transform point-of-care testing from rural clinics to urban households.
Thursday, 27th at 7:00 PM, Public House, Sukhumvit Soi 31
All BKKSci events are free of charge. We do however ask that you please consider supporting Public House by purchasing your choice of food and drink during the event. This is our way of thanking them for their support.
Also check out other Health & Wellness events in Nana Plaza, Arts events in Nana Plaza, Theatre events in Nana Plaza.
