# Event Details - **Event Name**: From Ion Channels to Cognition - **Event Start and End Date**: Tue, 17 Mar, 2026 at 04:00 pm - **Event Description**: From Ion Channels to Cognition: Multiscale Modeling of Brain Circuits under physiological and pathological conditions 17 marzo 2026 h 16:00 Aula Pacinotti, Scuola di Ingegneria Pisa Abstract: Understanding how higher brain functions emerge from cellular and subcellular processes remains one of the central challenges of modern neuroscience. In this seminar, I will present a computational approach that integrates experimentally constrained single-cell biophysics, realistic morphologies, and synaptic dynamics into large-scale network models capable of reproducing oscillatory regimes, spatiotemporal activation patterns, and information flow. I will discuss how detailed connectivity architectures and neuron-specific properties influence memory-related activity patterns and cognitive processes such as odor recognition and spatial navigation, and how perturbation of ion channel kinetics, synaptic strengths, and connectivity motifs, providing mechanistic insight into dysfunction associated with neurological and neurodegenerative conditions. Beyond basic neuroscience and technological advances, I will outline how biologically grounded neuronal models can inform translational strategies, including pharmacological target identification and the development of brain-inspired, explainable artificial intelligence systems. By bridging molecular mechanisms to systems-level computation, multiscale modeling offers a principled path toward understanding both normal cognition and its pathological alterations. Bio: Michele Migliore, PhD. He has been Research Director at the Institute of Biophysics of the Italian National Research Council (CNR-IBF, Palermo, Italy, 1983-2024), Director of the Palermo section of CNR-IBF (2015-2017), Visiting Professor of Computational Neuroscience at the University of Rome "La Sapienza" (Italy, 2018-2023), Visiting Professor of Cybernetics at the Department of Mathematics and Informatics of the University of Palermo (Italy, 2000-2018), and Visiting Scientist at the Department of Neuroscience of the Yale University School of Medicine (New Haven, USA, 2000-2020). His lab is involved in modelling realistic neurons and networks, synaptic integration processes, and plasticity mechanisms. The main long-term goal is to understand the emergence of higher brain functions and dysfunctions from cellular processes, implementing new tools and using state of the art simulation environments on different supercomputer systems - **Event URL**: https://allevents.in/pisa/from-ion-channels-to-cognition/200029786241652 - **Event Categories**: workshops, art, nonprofit, artificial-intelligence - **Interested Audience**: - total_interested_count: 2 ## Ticket Details ## Event venue details - **city**: Pisa - **state**: TO - **country**: Italy - **location**: Scuola di Ingegneria - Università di Pisa - **lat**: 43.7211762 - **long**: 10.3909509 - **full address**: Scuola di Ingegneria - Università di Pisa, Via Giunta Pisano, 2, 56122 Pisa PI, Italia, Pisa, Italy ## Event gallery - **Alt text**: From Ion Channels to Cognition - **Image URL**: https://cdn-az.allevents.in/events3/banners/386daf8c863282aeb9b6f5bb9e3a63caaf5c09972c303fc493bedf3b98b6f261-rimg-w1200-h675-dc3aa2da-gmir?v=1772966151 ## FAQs - **Q**: When and where is From Ion Channels to Cognition being held? - **A:** From Ion Channels to Cognition takes place on Tue, 17 Mar, 2026 at 04:00 pm to Tue, 17 Mar, 2026 at 04:00 pm at Scuola di Ingegneria - Università di Pisa, Via Giunta Pisano, 2, 56122 Pisa PI, Italia, Pisa, Italy. - **Q**: Who is organizing From Ion Channels to Cognition? - **A:** From Ion Channels to Cognition is organized by Dipartimento di Ingegneria dell'Informazione - Università di Pisa. - **Q**: Who is this event for? Is it right for me? - **A:** From Ion Channels to Cognition is ideal for curious learners, students, and skill-builders looking to gain hands-on knowledge and practical expertise in a focused, interactive setting. Whether you're a first-time attendee or a longtime enthusiast in Pisa, this event is thoughtfully curated to deliver a standout experience worth every moment. 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