

# Event Details

- **Event Name**: Emerging Neuroscientists Seminar Series:  Dr Dimokratis Karamanlis
- **Event Start and End Date**: Thu, 27 Nov, 2025 at 01:15 pm – Thu, 27 Nov, 2025 at 02:15 pm
- **Event Description**: The SWC are pleased to announced a Seminar by Dr Dimokratis Karamanlis, University of GenevaAbout this EventEmerging Neuroscientists Seminar Series:  Dr Dimokratis KaramanlisThis event will take place on Thursday 27 November 2025 at 13:15 (BST).The seminar will be held at 25 Howland Street, London, W1T 4JG. This central location provides easy access for attendees.Don't miss out on this informative and engaging event. Register now to secure your spot!Talk Title: Prefrontal correlates of a social learning strategy during joint decision-making in miceAbstract:Social animals often observe others to guide their behavior, strategically choosing when and from whom to learn. Although frontal cortical areas represent the actions and attributes of others, how these representations adapt to varying task demands and uncertainty remains unclear. Here, we investigated how mice use the actions of conspecifics during a goal-directed task and how the medial prefrontal cortex (mPFC) implements these social computations. In our novel design, pairs of mice are separated by a transparent divider and jointly perform a visually-guided, two-alternative forced-choice task. On a trial-by-trial basis, we independently varied the visual cue contrast for each mouse to create different levels of perceptual uncertainty. We observed that mice facing low-contrast stimuli reliably copied the decisions of partners with high-contrast cues, a stereotyped behavior consistent with a “copy when uncertain” strategy. This reliance on social information was abolished when the partner was replaced by a mechanical slider, confirming the social nature of the computation. Whole-brain c-Fos mapping revealed enhanced mPFC activation in mice performing the task jointly compared to those performing it solo, suggesting this region is a hub for integrating private sensory evidence with social information. Furthermore, large-scale electrophysiological recordings from mPFC identified choice-predictive neurons whose activity differed depending on whether the mouse initiated the decision or copied its partner. Our findings demonstrate that mice actively monitor conspecifics to guide actions under perceptual uncertainty and that task demands drive a flexible representation of social actions within the mPFC.  https://cdn-az.allevents.in/events9/banners/82bdfc10-b6ff-11f0-9b73-5188c4a9b9bd-rimg-w1200-h483-dc2b1b12-gmir.jpg Research ImageMaximum intensity projection of an 200-μm-deep imaging volume acquired with a light-sheet microscope. The image contains neurons in the prelimbic area of the mouse frontal cortex that were active during social decision-making.About the speaker:  Dimokratis KaramanlisDimos is currently a postdoctoral researcher in the lab of Sami El-Boustani at the University of Geneva. He originally studied medicine at the Aristotle University of Thessaloniki and completed his PhD on nonlinear signal processing in the retina with Tim Gollisch at the University Medical Center Göttingen. Dimos uses a combination of computational and experimental approaches to understand visual coding, how sensory signals are integrated into rapid decisions and how these signals are used to guide social learning.
- **Event URL**: https://allevents.in/london/emerging-neuroscientists-seminar-series-dr-dimokratis-karamanlis/100001703065738469
- **Event Categories**: workshops, performances, entertainment, it
- **Interested Audience**: 
  - total_interested_count: 0

## Ticket Details

- **Ticket URL**: https://consumer.pxf.io/c/1339408/3151484/39691?partnerpropertyid=1191892&MediaPartnerPropertyId=1191892&svlink=14105511&level=1&u=https%3A%2F%2Fwww.eventbrite.com%2Fe%2Femerging-neuroscientists-seminar-series-dr-dimokratis-karamanlis-tickets-1703065738469
- **Ticket Price Range**: min: 0, max: 0, currency: GBP

## Event venue details

- **city**: London
- **state**: EN
- **country**: United Kingdom
- **location**: Sainsbury Wellcome Centre
- **lat**: 51.52117379999999
- **long**: -0.1381206
- **full address**: Sainsbury Wellcome Centre, 25 Howland Street, London, United Kingdom

## Event Organizer details

- **affiliate_id**: 10
- **organizer**: The Sainsbury Wellcome Centre (SWC) (https://allevents.in/org/the-sainsbury-wellcome-centre-swc/23018245)

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## FAQs

- **Q**: When is the event happening?
  - **A:** Thu, 27 Nov, 2025 at 01:15 pm
- **Q**: Where is the event happening?
  - **A:** Sainsbury Wellcome Centre, 25 Howland Street, London, United Kingdom
- **Q**: What is the ticket price?
  - **A:** starting from 0 up to 0 GBP
- **Q**: Who is organizing the event?
  - **A:** The Sainsbury Wellcome Centre (SWC)
- **Q**: What type of event is this?
  - **A:** workshops, performances, entertainment, it
- **Q**: Where can I find ticket details about Emerging Neuroscientists Seminar Series:  Dr Dimokratis Karamanlis ?
  - **A:** You can find ticket details about this event on AllEvents.

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