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22nd European Congress on Alternatives to Animal Testing

22nd European Congress on Alternatives to Animal Testing

Europe's oldest and biggest scientific congress on the 3Rs - Refine - Reduce - Replace

Topics / tentative sessions

► Refinement: best practice approaches, animal welfare, avoidance of severe suffering, culture of care
► Reduction: transparency, reproducibility and translational aspects (species differences)
► Replacement: advanced technologies for implementing the 3Rs: bio-printing, -omics technologies, systems biology approaches, IT and big data
► Banning the 90-day dog study for the safety testing of human drugs and pharmaceuticals
► 3Rs in education and academia
► 3R Centers in Europe & international - national and local centers
► International progress in 3Rs research: New Funding Initiatives & Global Cooperation
► 3D Models & multi-organ-chips (MOC), human-organ-chips (HOC)
► Biological barriers: e.g. lung, gut, kidney & skin epithelia, blood-brain & blood-saliva barriers
► In Silico Models: toxicology & efficacy of drugs, chemicals & cosmetics, new approaches for biomedical research
► Disease models using HUMAN cells, tissues and organs
► Efficacy and safety testing of drugs, medical devices & biopharmaceutics (incl. vaccines, blood components, allergenics, somatic cells, gene therapies, tissues and living cells used in therapy)
► REACH - the most frequently used alternatives: Read Across, WoE (Weight of Evidence), QSAR
► Advanced safety testing of cosmetics and consumer products (e. g. toys)
► Alternatives to animal testing in food safety, nutrition and efficacy
► Specific Endpoints of Toxicity: repeated-dose toxicity, inhalation, sensitization, reproductive & developmental toxicity (mEST & hEST), carcinogenesis, nanotoxicology
► Neurotoxicity & Developmental Neurotoxicity (DNT)
► Ecotoxicology
► Stem cell models and technology (hIPS, ES, mES, mIPS…)
► Implementing EU Dir 63/2010 - update
► Ethical & legal issues
► Advanced GMO models – CRISPR/Cas in vivo & in vitro
► Initiative for Implementing Serum Free Culture Media
► Publication policies regarding animal experiments and the 3Rs principles
► An integrated interdisciplinary approach to animal-free nanomaterial and chemical safety assessment: Results of the in3 project
► Vaccines: safety testing & the 3Rs
► "Young Scientists" session
► Free communications

Map JKU - Johannes Kepler Universität Linz, Altenberger Straße 69, 4040 Linz, Austria, Linz, Austria
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