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ASCPT2020: PBPK with PK-Sim & MoBi (OSP Suite)

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ASCPT2020: PBPK with PK-Sim & MoBi (OSP Suite)


esqLABS, in collaboration with the University of Houston, College of Ph*rm*cy, is running two hands-on PK-Sim® & MoBi® workshops on PBPK and PBPK-based QSP on Monday and Tuesday 16th and 17th of March 2020 (pre ASCPT) at the University of Houston

The workshops cover the basics of PBPK and concepts and application of combining PK-Sim, MoBi and R to build your very own digital platforms for the prediction of clinical trial outcomes by leveraging physiological and mechanistic knowledge to translate early in-vitro and preclinical outcomes to the clinic.

Within the two workshops, you will learn how to:

Workshop 1 / Day 1:


Build a PBPK model in PK-Sim and compare to observed data

Learn how to model drug-drug interactions in PK-Sim (DDI)

Learn how to consider age-dependency in drug PK in PK-Sim (Pediatric Analyses)

Conduct population simulations in PK-Sim and MoBi


Workshop 2 /Day 2:


Integrate mechanism-based pharmacodynamics in MoBi

Conduct parameter identifications in PK-Sim and MoBi

Simulate and analyze your PBPK-QSP model in R


The two workshops will be held by the consultants and scientists from esqlabs GmbH with extensive experience in the use of PK-Sim® & MoBi® in all application areas.

While the workshop does not require any prior experience with PK-Sim® & MoBi®, many topics will be of interest even for advanced users.

LOCATION

Just a 10-min ride from the ASCPT2020 conference hotel (Marriot Marquis):

University of Houston, Department of Pharmacological and Pharmaceutical Sciences4849 Calhoun RdPharmacy Hall, Health Building (HB) 2, Room 3001Houston, Texas 77204-5037United States

REGISTRATION

You can register for each workshop (days) separately or for both at a reduced price.

Each workshop day is currently restricted to 15 external participants.

Registration includes coffee- and lunch breaks.

AGENDA

The use-cases within the workshops will be based on published examples.

We will develop PBPK models for small molecules for DDI and pediatric populations and PBPK models for biologics (antibody-drug conjugates (AsDC)), which we develop into a PB-QSP model for treatment of tumor growth.

The two workshop days are scheduled as follows:

Day 1


Day 2


PREPARATION



BRING YOUR OWN LAPTOPS, pre-installed with the software! We will be doing hands-on work!



To download the software, please click here



Download & install the R distribution (Ver 3.5+) from here



Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here



For starters, please check out the tutorial site (videos & hands-on) here



NOTES


Please add this site to your watchlist (very top of page) to be informed of any changes.


Visit our News & Events Section for info on additional workshops in the future and news on our future developments in physiologically-based quantitative-systems-pharmacology.


Best Regards,

Stephan Schaller (Managing Director, esqLABS GmbH)
Ticket Information Ticket Price
Full DAY 1 EUR 500
Full DAY 2 EUR 500
Full 2-Day Workshop EUR 750

Tickets

Tickets for ASCPT2020: PBPK with PK-Sim & MoBi (OSP Suite) can be booked here.



Also check out other Workshops in Houston, Business Events in Houston, Conferences in Houston.

Map University of Houston, Department of Pharmacological and Pharmaceutical Sciences, 4849 Calhoun Rd, Houston, United States
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